单细胞组学案例文章

英文题目期刊影响因子（发表时）中科院分区发表年份合作单位领域物种组织类型平台
Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathwayCell Death Discov72区2023中山大学第五医院医学小鼠肾脏DG1000
Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruptionRespiratory Research5.82区2023山东第一医科大学第一附属医院医学小鼠肺组织分选细胞DG1000
Temporospatial hierarchy and allele-specific expression of zygotic genome activation revealed by distant interspecific urochordate hybridsNature Communications14.71区2024中国海洋大学动物玻璃海鞘、萨式海鞘杂交种64细胞期、112细胞期和早期神经胚发育阶段胚胎DG1000
Histological and Single-nucleus Transcriptome Analyses Unveil the Specialized Functions of Ligular Sclerenchyma Cells and Key Regulators of Leaf Angle in MaizeMolecular Plant17.11区2024山东农业大学和北大现代农业研究院植物玉米叶枕DG1000
Integrative multi-omics analysis reveals the role of tumor-associated endothelial cells and their signature in prognosis of intrahepatic cholangiocarcinomaJournal of Translational Medicine6.12区2024中国人民解放军医学院医学人1例肝内胆管癌+5例公共数据DG1000
Cross-species single-cell analysis reveals divergence and conservation of peripheral blood mononuclear cellsBMC Genomics3.52区2024华南农业大学动物黄颡鱼、许氏平鮋、鸡、鳖、人、小鼠12个物种PBMC 黄颡鱼、许氏平鮋、鸡、鳖、人、小鼠(n=2)DG1000
Spatial and single-cell transcriptomics reveal cellular heterogeneity and a novel cancer-promoting Treg cell subset in human clear-cell renal cell carcinomaJournal for ImmunoTherapy of Cancer10.31区2025第四军医大学医学人肾透明细胞癌患者手术切除肿瘤组织（n=4）DG1000、S1000
Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCCFrontiers in immunology5.72区2025第四军医大学医学肾透明细胞癌患者手术切除肿瘤组织DG1000、S1000
Insight into perfluorooctanoic acid-induced impairment of mouse embryo implantation via single-cell RNA-seqJournal of Hazardous Materials12.21区2025温州医科大学附属第二医院医学小鼠子宫DG1000
Origin and stepwise evolution of vertebrate lungsnature ecology & evolution14.11区2025西北工业大学 第四军医大学动物多鳍鱼、非洲肺鱼脑、食管、 鳃、心脏、肠道、肾脏、肝脏、肌肉、皮肤、胃DG1000
Machine learning-based prediction reveals kinase MAP4K4 regulates neutrophil differentiation through phosphorylating apoptosis-related proteinsPLoS Computational Biology3.82区2025四川大学华西第二医院医学小鼠骨髓DG1000
Broflanilide induces zebrafish neurobehavioral defects by interfering with synaptic homeostasisAquatic Toxicology4.13区2025沈阳农业大学动物斑马鱼暴露毒素第30天斑马鱼脑（10只雌性，10只雄性样本混合在一起）DG1000
Single-cell nuclear transcriptomics reveal root tip adaptations to nitrogen scarcity in wheatthe crop journal5.61区2025西北农林科技大学、河南省农业科学院植物小麦对照组根（n=3）以及氮营养不足组根（n=3）DG1000
Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacementFrontiers in Immunology5.92区2025成都中医药大学、临沂市人民医院、山东大学齐鲁医学院医学小鼠脑溢血老年小鼠（n=3）以及置换小胶质细胞的脑溢血老年小鼠（n=3）DG1000
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemiaCell Host & Microbe18.71区2025华中科技大学同济医学院附属同济医院医学小鼠MCAO以及 L.a+MCAO脑缺血小鼠脑DG1000
The Liquid Crystal Monomer 3cH2B Affects the Visual System via Neural-Cell-Specific Retinoic Acid Disruption in the Optic TectumEnvironmental Science & Technology11.31区2025沈阳农业大学植物保护学院、中国农业科学院农产品质量标准与检测技术研究所、中国水产科学研究院淡水渔业研究中心动物斑马鱼活体、眼睛、大脑等DG1000、S1000
Spatial transcriptome analysis of tea tender shoot Spatial transcriptome analysis of the tea tender shoot sheds light on transcriptional regulation of characteristic metabolitesHorticulture Research8.51区2026福建农林大学植物茶树10X
Super-resolution multimodal spatial transcriptomics reveals an ovoid stem-cell niche structuring de novo shoot regenerationMolecular Plant24.11区2026北京大学现代农业研究院植物番茄6日龄幼苗子叶S1000/S3000+DG1000+ISSeq+Stereo‑seq+10×Xenium