BMK Launches an FFPE Spatial Transcriptomics Product: Direct poly(A) Capture Breaks Through the Bottleneck of Clinical Sample Detection

BMKMANU S3000-FFPE Spatial Transcriptomics Platform

Overview of S3000-FFPE Spatial Transcriptomics Platform

FFPE samples, the most prevalent sample type in clinical pathology, harbor invaluable biological information. However, inherent RNA degradation and protein-nucleic acid crosslinking induced by formalin fixation create substantial barriers to unlocking their rich molecular information.

BMKMANU S3000-FFPE spatial transcriptomics platform innovatively adopts a proprietary poly(A) capture technology together with a patented de-crosslinking solution, precisely overcoming the key challenges of RNA degradation and protein-nucleic acid crosslinking. With high specificity and capture efficiency for mRNA , it offers an effective approach for whole transcriptome profiling of FFPE samples across diverse species.

Challenges of Spatial Transcriptomics for FFPE Samples